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Myoglobin Antibody

Rabbit Monoclonal Antibody

  • WB - Myoglobin Antibody AJ1520b
    A. Western blot analysis on human heart tissue lysate using anti-myglobin RabMAb (Cat. #AJ1520b).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P02144
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names EP3080
Calculated MW 17184 Da
Gene ID 4151
Other Names Myoglobin, MB
Target/Specificity A synthetic peptide corresponding to residues near the N-terminus of human myglobin was used as an immunogen.
Dilution WB~~1:500~2000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMyoglobin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MB
Function Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
Research Areas
Citations (0)

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Myoglobin, an intracellular haemoprotein expressed in the heart and oxidative skeletal myofibres of vertebrates, binds molecular oxygen and may facilitate oxygen transport from erythrocytes to mitochondria, thereby maintaining cellular respiration during periods of high physiological demand (1). Myoglobin may serve a variety of functions in muscular oxygen supply, such as oxygen storage, facilitated O(2) diffusion, and myoglobin-mediated oxidative phosphorylation. Disruption of myoglobin results in the activation of multiple compensatory mechanisms that steepen the pO(2) gradient and reduce the diffusion path length for O(2) between capillary and the mitochondria (2).


1. Garry DJ, et al. Nature, 396(6705):905-8, 1998 2. Godecke A, et al. Proc Natl Acad Sci, 96(18):10495-500, 1999

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Cat# AJ1520b
(40 western blots)
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