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Neurofilament M AntibodyRabbit Monoclonal Antibody
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AJ1532a | 100ul 400 ul | 2-3 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
Neurofilament M Antibody - Product info | |
| Application | WB, IHC, IF
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| Primary Accession | P07197 |
| Reactivity | Human |
| Clone Names | EP2460 |
| Calculated MW | 102472 Da |
| Gene ID 4741 | |
| Other Names NEFM, NEF3, NFM, Neurofilament medium polypeptide, Neurofilament triplet M protein;160 kDa neurofilament protein;Neurofilament 3 | |
| Target/Specificity A synthetic peptide corresponding to residues in human Neurofilament M was used as an immunogen. | |
| Dilution WB~~1:1000~10000 IHC~~1:250~500 | |
| Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions Neurofilament M Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
Neurofilament M Antibody - Protein Information | |
| Name NEFM | |
| Synonyms NEF3, NFM | |
| Function Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber | |
Neurofilament M Antibody - Application data
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Western blot analysis on (A) 293T and (B) SH-SY5Y cell lysates using anti-Neurofilament M RabMAb (Cat. #AJ1532a).
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Immunohistochemical analysis of paraffin-embedded human normal brain tissue using anti-Neurofilament M RabMAb (Cat. #AJ1532a).
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Immunohistochemical analysis of paraffin-embedded human glioma using anti-Neurofilament M RabMAb (Cat. #AJ1532a).
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Immunofluorescent staining of SH-SY-5Y cells using anti-Neurofilament M RabMAb (Cat. #AJ1532a).
Neurofilament M Antibody - Related products
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BACKGROUND
Neuofilaments (NF) are members of the intermediate filament protein family also known as 10nm filaments. These neuron-specific filaments are the major constituents of the axonal cytoskeleton (1). NFs are composed of three major proteins; NF-H, NF-M and NF-L and the ratio of each protein changes during neuronal development. NF-H is the heavy molecular weight protein (200 kDa), NF-M the medium (160 kDa) and NF-L the light protein (68kDa) (2).
REFERENCES
1. Nixon, R.A., et al. Cell Motil. Cytoskeleton 22, 81-91, 1992 2. Julien, JP., et al. Brain Res. 387, 243-250, 1986
