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OCT2 Antibody

Rabbit Monoclonal

  • WB - OCT2 Antibody AJ1558c
    A.Western blot analysis on Daudi lysate using anti-Oct-2 RabMAb (Cat. #AJ1558c).
  • IHC - OCT2 Antibody AJ1558c
    B. Immunohistochemical analysis of paraffin-embedded human tonsil using anti-Oct-2 RabMAb (Cat. #AJ1558c).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P09086
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names EPR542
Calculated MW 51209 Da
Gene ID 5452
Other Names POU domain, class 2, transcription factor 2, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, Octamer-binding protein 2, Oct-2, Octamer-binding transcription factor 2, OTF-2, POU2F2, OCT2, OTF2
Target/Specificity A synthetic peptide corresponding to residues in human Oct.-2 was used as an immunogen.
Dilution WB~~1:5000~10000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOCT2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name POU2F2
Synonyms OCT2, OTF2
Function Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter.
Cellular Location Cytoplasm. Nucleus.
Tissue Location Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147
Citations (0)

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Octamer transcription factor-2 (Oct-2) is a transcription factor that specifically binds to the octamer motif (5- ATTTCAT-3). Mostly expressed in B cells, Oct-2 possess a leucine zipper domain and belongs to the POU family of transcription factors (1-3). Additionally, Oct-2 regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression.


1. Staudt, L. M., et al. Nature (London) 323, 640, 1986 2. Scheidereit, C., et al. Cell 51, 783, 1987 3. Herr, W. et al. Genes Dev. 9, 1679, 1995

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Cat# AJ1558c
(40 western blots)
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