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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   OX40L Antibody   

OX40L Antibody

Rabbit Monoclonal Antibody

  • WB - OX40L Antibody AJ1561b
    A. Western blot analysis on recombinant OX40L using anti-OX40L RabMAb (Cat. #AJ1561b), dilution 1:50,000. A) 10ng/lane and B) 5ng/lane of recombinant protein was loaded on the membrane
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P23510
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names EP1168Y
Calculated MW 21050 Da
Gene ID 7292
Other Names Tumor necrosis factor ligand superfamily member 4, Glycoprotein Gp34, OX40 ligand, OX40L, TAX transcriptionally-activated glycoprotein 1, CD252, TNFSF4, TXGP1
Target/Specificity A synthetic peptide corresponding to residues on the C-terminus of human OX40L was used as an immunogen.
Dilution WB~~1:10000~50000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOX40L Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms TXGP1
Function Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.
Cellular Location Membrane; Single-pass type II membrane protein
Research Areas
Citations (0)

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Tumor necrosis factor receptor superfamily member 4 (OX40, CD134) is a membrane receptor found on activated CD4+ and CD8+ T cells and B cells (1). OX40 binds to OX40 ligand (OX40L) and other TNF receptor-associated factors (TNAF2, TRAF3, TRAF5). OX40-OX40L complex produces CD28 independent co-stimulatory signals. OX40 is involved in the pathologic cytokine storm associated in certain viral infection, such as H4N1 bird flu. OX40 starts a survival signal to the T-cell preventing activation-induced apoptosis, but up regulates cytokine production. Inhibition of OX40 using OX40-immunoglobulin has been linked to reduction of immune overreaction without affecting the viral clearance (2).


1. Gramaglia I, et al. Immunol 161:6510-6517, 1998.
2. Humphreys IR, et al. JEM 198:1237-1242, 2003

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Cat# AJ1561b
(40 western blots)
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