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p115 Antibody

Rabbit Monoclonal Antibody

  • WB - p115 Antibody AJ1562a
    A. Western blot analysis on A) HeLa, B) 293T, C) HepG2, D) Cos cell lysates using anti- p115 RabMAb (Cat. #AJ1562a), 1:500 dilution.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O60763
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal
Clone Names EPR2140Y
Calculated MW 107895 Da
Gene ID 8615
Other Names General vesicular transport factor p115, Protein USO1 homolog, Transcytosis-associated protein, TAP, Vesicle-docking protein, USO1, VDP
Target/Specificity A synthetic peptide corresponding to residues near the N-terminus of human p115 was used as an immunogen.
Dilution WB~~1:500
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautionsp115 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name USO1
Synonyms VDP
Function General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity (By similarity).
Cellular Location Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein. Note=Recycles between the cytosol and the Golgi apparatus during interphase. During interphase, the phosphorylated form is found exclusively in cytosol; the unphosphorylated form is associated with Golgi apparatus membranes
Research Areas
Citations (0)

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p115 / TAP (Vesicle docking protein p115, Transcytosis-associated protein) is a general vesicular transport factor located in the Golgi complex. p115 is part of the Golgin protein family, defined by their location in the Golgi matrix and their long coiled-coil domain. p115 is thought to be essential for ER to Golgi traffic (1). Specifically, p115 is required for intercisternal transportation within the Golgi stack and required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane (2). Also, p115 has been suggested to be act as a vesicular anchor to the target membrane.


1. Alvarez C et al., JBC 276(4):2693-2700, 2001.
2. Shorter J, Warren G et al., JBC 146(1):57-70, 1999.

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Cat# AJ1562a
(40 western blots)
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