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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   p16-Arc Antibody (N-term)   

p16-Arc Antibody (N-term)

Rabbit Monoclonal Antibody

  • WB - p16-Arc Antibody (N-term) AJ1566a
    A. Western blot analysis on fetal brain lysate using anti-p16 Arc RabMAb (Cat. #AJ1566a), dilution 1:20,000
  • IHC - p16-Arc Antibody (N-term) AJ1566a
    B. Immunohistochemical analysis of paraffin-embedded human uterus adenocarcinoma using anti-p16-ARC RabMAb (Cat. #AJ1566a).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15511
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal
Clone Names EP1551Y
Calculated MW 16320 Da
Gene ID 10092
Other Names Actin-related protein 2/3 complex subunit 5, Arp2/3 complex 16 kDa subunit, p16-ARC, ARPC5, ARC16
Target/Specificity A synthetic peptide corresponding to residues on the N-terminus of human p16-ARC was used as an immunogen.
Dilution WB~~1:1000~10000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautionsp16-Arc Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARPC5
Synonyms ARC16
Function Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Cellular Location Cytoplasm, cytoskeleton. Cell projection
Research Areas
Citations (0)

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The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells. The human complex consists of seven subunits which include the actin related proteins Arp2 and Arp3, and five others referred to as p41-Arc, p34-Arc, p21-Arc, p20-Arc, and p16-Arc (p complex) (1). These proteins localize in the cytoplasm of fibroblasts that lack lamellipodia, but are enriched in lamellipodia on stimulation with serum or platelet-derived growth factor. A dynamic role for this complex in the organization of the actin cytoskeleton has been suggested (2). p16-Arc has been found to be a globular alpha-helical subunit (3).


1. Welch MD, et al. J Cell Biol 138(2):375-84, 1997
2. Machesky LM, et al. Biochem J. 328(Pt1):105-12, 1997
3. Robinson RC, et al. Science 294(5547):1679-84, 2001

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Cat# AJ1566a
(40 western blots)
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