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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Prolactin Antibody   

Prolactin Antibody

Rabbit Monoclonal Antibody

  • WB - Prolactin Antibody AJ1657a
    Western blot analysis on (A) Prolactin recombinant protein and (B) fetal pituitary lysates using anti-Prolactin RabMAb (Cat. #AJ1657a).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01236
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names EPR3216
Calculated MW 25876 Da
Gene ID 5617
Other Names Prolactin, PRL, PRL
Target/Specificity A synthetic peptide corresponding to residues in human Prolactin was used as an immunogen.
Dilution WB~~1:50000(5ng)
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsProlactin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRL
Function Prolactin acts primarily on the mammary gland by promoting lactation.
Cellular Location Secreted.
Research Areas
Citations (0)

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Prolactin (PRL) is a peptide hormone secreted from the anterior pituitary gland, primarily associated with lactation. It plays an important role in the proliferation and differentiation of cells in mammary gland development (1, 2). It also participates in regulation of angiogenesis (3). PRL has more actions than all other pituitary hormones combined. The initial step in the action of PRL, like all other hormones, is the binding to a specific membrane receptor, the PRL receptor (PRLR). Pituitary PRL acts via a classic endocrine pathway (2). The PRL that is produced by many different cell types can act in a more direct fashion; i.e., as a growth factor, neurotransmitter or immunomodulator, in an autocrine or paracrine manner. Thus, locally produced PRL can act on adjacent cells (paracrine) or on the PRL-secreting cell itself (autocrine) in many tissues via the broad distribution of its receptors (2, 4).


1. Brisken et al. Dev. Cell. 3:877-887; 2002 2. Bole-Feysot et al. Endor. Rev. 19:225-268; 1998 3. Struman et al. Proc. Natl. Acad. Sci. USA 96:1246-1251; 1999 4. Goffin et al. Annu. Rev. Physiol. 64 :47-67 ; 2002

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Cat# AJ1657a
(40 western blots)
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