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Prostate-Specific Antigen (PSA) Antibody

Rabbit Monoclonal Antibody

  • WB - Prostate-Specific Antigen (PSA) Antibody AJ1659a
    A. Western blot analysis on human prostate carcinoma tissue lysate using anti-PSA RabMAb (Cat. #AJ1659a), dilution 1:10,000.
  •  - Prostate-Specific Antigen (PSA) Antibody AJ1659a
    B. Immmunohistochemical analysis of paraffin-embedded human prostate carcinoma using anti-PSA RabMAb (Cat. #AJ1659a)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P07288
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names EP1588Y
Calculated MW 28741 Da
Gene ID 354
Other Names Prostate-specific antigen, PSA, Gamma-seminoprotein, Seminin, Kallikrein-3, P-30 antigen, Semenogelase, KLK3, APS
Target/Specificity A synthetic peptide corresponding to residues near the C-terminal of human PSA.
Dilution WB~~1:1000~10000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsProstate-Specific Antigen (PSA) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KLK3
Synonyms APS
Function Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
Cellular Location Secreted.
Research Areas
Citations (0)

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Prostate-specific antigen (PSA, Kallikrein-3, KLK3) is a serine protease that is usually secreted from the prostate gland and presented in seminal plasma. PSA function in the liquefaction of seminal coagulum, through hydrolysis of the high molecular mass seminal vesicle protein. Its substrates includes semenogelin I & II, fibronectin, insulin-like growth factor binding protein 3 (IGBP3), and laminin (1). Highly expressed by normal and malignant prostate cancer cells, PSA has been implicated in the growth, invasion, and metastasis of prostate cancer cells (2). Therefore, PSA is widely used as a diagnostic marker for prostate cancer. Recently, PSA has been suggested as an endothelial cell-specific inhibitor of angiogenesis (3).


1. K Tazawa K et al. Path Intl 49(6):500-505, 1999
2. MG Lawerence MG et al. Cells Tissues Organs 185:111-115, 2007;
3. Siddiqui IA et al. Carcinogenesis 27(4):833-839, 2006.

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Cat# AJ1659a
(40 western blots)
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