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>   home   >   Products   >   Primary Antibodies   >   Metabolism   >   SAA4 Antibody   

SAA4 Antibody

Rabbit Monoclonal Antibody

  • WB - SAA4 Antibody AJ1703a
    Western blot analysis on human plasma using anti-SAA4 RabMAb (Cat. #AJ1703a).
  • IHC - SAA4 Antibody AJ1703a
    Immunohistochemical analysis of paraffin-embedded normal kidney tissue using anti-SAA4 RabMAb (Cat. #AJ1703a).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35542
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names EPR2926
Calculated MW 14747 Da
Gene ID 6291
Other Names Serum amyloid A-4 protein, Constitutively expressed serum amyloid A protein, C-SAA, SAA4, CSAA
Target/Specificity A synthetic peptide corresponding to residues in human SAA4 was used as an immunogen.
Dilution WB~~1:10000~20000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSAA4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SAA4
Synonyms CSAA
Function Major acute phase reactant. Apolipoprotein of the HDL complex.
Cellular Location Secreted.
Tissue Location Expressed by the liver; secreted in plasma.
Research Areas
Citations (0)

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Serum amyloid A (SAA) proteins are family of apolipoproteins of high density lipoprotein (HDL). They can be separated into two distinct groups. First group (SAA1, SAA2, and SAA3) consists of acute phase reactant whose expression level increase in the blood in a response to trauma, infection, inflammation, and neoplasia. These acute phase SAAs associates with HDL during inflammation and remodel the HDL particle by displacing Apo-A1. The second distinct group consists of SAA4 and SAA5 which exist as the minor apolipoproteins on HDL, but this group of SAA constitutes more than 90% of all the SAA during homeostasis, and it is thought to play a role in the normal functioning of the HDL particle (1, 2). The distribution of SAA4 is restricted to two lipoprotein subclasses; therefore, SAA4 has been suggested be a factor in lipid transfer between lipoprotein classes. SAA4 mRNA and protein expression in macrophage-derived foam cells of coronary and carotid arteries suggested a specific role of SAA4 during inflammation including atherosclerosis (3).


1. O Gutfeld et al., JHC 54 (1): 63-73, 2006. 2. MC de Beer et al., J Lipid Res. 36:526-534, 1995. 3. A Hrzenjak et al., Protein Engineering 14(12):949-952, 2001.

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Cat# AJ1703a
(40 western blots)
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