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SCARF1 Antibody

Rabbit Monoclonal Antibody

  • WB - SCARF1 Antibody AJ1707a
    Western blot analysis on (A) human placenta and (B) fetal heart lysates using anti-SCARF1 RabMAb (Cat. #AJ1707a).
  • IHC - SCARF1 Antibody AJ1707a
    Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-SCARF1 RabMAb (Cat. #AJ1707a).
  • IHC - SCARF1 Antibody AJ1707a
    Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-SCARF1 RabMAb (Cat. #AJ1707a).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14162
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names EPR3848
Calculated MW 87387 Da
Gene ID 8578
Other Names Scavenger receptor class F member 1, Acetyl LDL receptor, Scavenger receptor expressed by endothelial cells 1, SREC-I, SCARF1, KIAA0149, SREC
Target/Specificity A synthetic peptide corresponding to residues in human SCARF1 was used as an immunogen.
Dilution WB~~1:1000~10000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSCARF1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA0149, SREC
Function Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Endothelial cells.
Research Areas
Citations (0)

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Scavenger receptor class F member 1 (SCARF1) mediates the selective uptake of modified low density lipoprotein (LDL), such as acetylated LDL and oxidized LDL, into endothelial cells (1). It also mediates heterophilic interactions, suggesting that it functions as an adhesion protein (2). SCARF1 has several characteristic domain structures; an N-terminal extracellular domain with seven epidermal growth factor (EGF)-like cysteine pattern signatures, and an unusually long C-terminal cytoplasmic domain composed of a Ser/Pro-rich region followed by a Gly-rich region. SCARF1 is expressed at high levels in endothelial cells but not in smooth muscle cells (1).


1. Hideki Adachi, et al. The Journal of Biological Chemistry, 277:24014-24021, 2002 2. The UniProt Consortium. The Universal Protein Resource (UniProt). Nucleic Acids Res. 36:D190-D195 (2008)

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Cat# AJ1707a
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