|Reactivity||Human, Mouse, Rabbit, Hamster, Monkey, Pig, Bovine, Dog|
|Dilution||IHC-P (6-9 µg/ml)|
|Other Names||G-protein coupled receptor 6, Sphingosine 1-phosphate receptor GPR6, GPR6|
|Target/Specificity||Human GPR6. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR12 (60%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||GPR6 Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein Note=Detected in the intracellular compartments. It is currently unclear whether this is a cell surface or intracellular receptor|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity).
Heiber M.,et al.DNA Cell Biol. 14:25-35(1995).
Song Z.-H.,et al.Genomics 28:347-349(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Uhlenbrock K.,et al.Cell. Signal. 14:941-953(2002).
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