NPBWR1 / GPR7 Antibody (Cytoplasmic Domain)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, E |
---|---|
Primary Accession | P48145 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 36kDa |
Dilution | IHC-P (20 µg/ml) |
Gene ID | 2831 |
---|---|
Other Names | Neuropeptides B/W receptor type 1, G-protein coupled receptor 7, NPBWR1, GPR7 |
Target/Specificity | Human NPBWR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
Precautions | NPBWR1 / GPR7 Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NPBWR1 |
---|---|
Synonyms | GPR7 |
Function | Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B. |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | Found in cerebellum and frontal cortex. Detected at high levels in hippocampus, amygdala and trachea; at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high levels in lung carcinoma |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.
References
O'Dowd B.F.,et al.Genomics 28:84-91(1995).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Brezillon S.,et al.J. Biol. Chem. 278:776-783(2003).
Tanaka H.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:6251-6256(2003).
Sjoeblom T.,et al.Science 314:268-274(2006).
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