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MTNR1A / Melatonin Receptor 1a Antibody (Cytoplasmic Domain)

Rabbit Polyclonal Antibody

     
  • IHC - MTNR1A / Melatonin Receptor 1a Antibody (Cytoplasmic Domain) ALS10066
    Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P48039
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 39kDa
Dilution IHC-P (5-10 µg/ml)
Additional Information
Gene ID 4543
Other Names Melatonin receptor type 1A, Mel-1A-R, Mel1a receptor, MTNR1A
Target/Specificity Human MTNR1A. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsMTNR1A / Melatonin Receptor 1a Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MTNR1A
Function High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). Hippocampus
Research Areas
Citations (0)

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Background

High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.

References

Reppert S.M.,et al.Neuron 13:1177-1185(1994).
Ebisawa T.,et al.Biochem. Biophys. Res. Commun. 262:832-837(1999).
Huang Y.-H.,et al.Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS10066
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