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OPRD1 / Delta Opioid Receptor Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - OPRD1 / Delta Opioid Receptor Antibody (N-Terminus) ALS10068
    Anti-Delta Opioid Receptor antibody ALS10068 IHC of human brain, neurons and glia.
    detail
  • IHC - OPRD1 / Delta Opioid Receptor Antibody (N-Terminus) ALS10068
    Anti-OPRD1 / Delta Opioid Receptor antibody IHC of human Skin, Melanoma.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P41143
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 40kDa
Dilution IHC-P (4-38 µg/ml)
Additional Information
Gene ID 4985
Other Names Delta-type opioid receptor, D-OR-1, DOR-1, OPRD1, OPRD
Target/Specificity Human Delta Opioid Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsOPRD1 / Delta Opioid Receptor Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OPRD1
Synonyms OPRD
Function G-protein coupled receptor that functions as a receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Detected in oocytes (at protein level). Detected in brain cortex, hypothalamus, hippocampus and olfactory bulb. Detected in oocytes.
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.

References

Knapp R.J.,et al.Life Sci. 54:PL463-PL469(1994).
Knapp R.J.,et al.Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
Simonin F.,et al.Mol. Pharmacol. 46:1015-1021(1994).
Kaighin V.A.,et al.Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).

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$ 467.50
Cat# ALS10068
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