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PTHR2 / PTH2R Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - PTHR2 / PTH2R Antibody (C-Terminus) ALS10077
    Anti-PTH2R / PTHR2 antibody ALS10077 IHC of human brain, neurons and glia.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P49190
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 62kDa
Dilution IHC-P (11-28 µg/ml)
Additional Information
Gene ID 5746
Other Names Parathyroid hormone 2 receptor, PTH2 receptor, PTH2R, PTHR2
Target/Specificity Human PTH2R / PTHR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsPTHR2 / PTH2R Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTH2R
Synonyms PTHR2
Function This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed abundantly in brain and pancreas. Also expressed in the testis.
Volume 50 µl
Research Areas
Citations (0)

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Background

This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor (By similarity).

References

Usdin T.B.,et al.J. Biol. Chem. 270:15455-15458(1995).
King M.M.,et al.Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
Usdin T.B.,et al.Genomics 37:140-141(1996).
John M.R.,et al.Endocrinology 143:1047-1057(2002).

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$ 395.00
Cat# ALS10077
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