|Dilution||IHC-P (2.8-4.6 µg/ml)|
|Other Names||Proteinase-activated receptor 3, PAR-3, Coagulation factor II receptor-like 2, Thrombin receptor-like 2, F2RL2, PAR3|
|Target/Specificity||Human F2RL2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except F2R (42%), F2RL1 (37%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||F2RL2 / PAR3 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
Ishihara H.,et al.Nature 386:502-506(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Schmutz J.,et al.Nature 431:268-274(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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