|Reactivity||Human, Mouse, Hamster, Monkey, Pig, Horse, Bovine, Dog|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||G-protein coupled receptor 12, GPR12|
|Target/Specificity||Human GPR12 / GPCR12. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||GPR12 Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production.
Song Z.-H.,et al.Genomics 28:347-349(1995).
Dunham A.,et al.Nature 428:522-528(2004).
Uhlenbrock K.,et al.Cell. Signal. 14:941-953(2002).
Yin H.,et al.J. Biol. Chem. 284:12328-12338(2009).
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