|Application ||IHC-P, E|
|Dilution||IHC-P (5 µg/ml)|
|Other Names||C-C chemokine receptor type 8, C-C CKR-8, CC-CKR-8, CCR-8, CC chemokine receptor CHEMR1, CMKBRL2, Chemokine receptor-like 1, CKR-L1, GPR-CY6, GPRCY6, TER1, CDw198, CCR8, CKRL1, CMKBR8, CMKBRL2|
|Target/Specificity||Human CCR8. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||CCR8 Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CKRL1, CMKBR8, CMKBRL2|
|Function||Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection.
Zaballos A.,et al.Biochem. Biophys. Res. Commun. 227:846-853(1996).
Samson M.,et al.Eur. J. Immunol. 26:3021-3028(1996).
Tiffany H.L.,et al.J. Exp. Med. 186:165-170(1997).
Napolitano M.,et al.J. Immunol. 157:2759-2763(1996).
Nakajima T.,et al.Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
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