|Application ||IHC-P, E|
|Reactivity||Human, Monkey, Pig, Horse, Bovine, Dog|
|Dilution||IHC-P (5-10 µg/ml)|
|Other Names||G-protein coupled receptor family C group 5 member B, A-69G12.1, Retinoic acid-induced gene 2 protein, RAIG-2, GPRC5B, RAIG2|
|Target/Specificity||Human GPRC5B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||RAIG2 / GPRC5B Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.|
|Cellular Location||Cell membrane; Multi-pass membrane protein Cytoplasmic vesicle membrane; Multi- pass membrane protein Note=Localized in the plasma membrane and perinuclear vesicles|
|Tissue Location||Expression is high in kidney, pancreas, and testis, medium in brain, heart, prostate, small intestine, and spleen, low in liver, placenta, skeletal muscle, colon, ovary, and thymus, and not detectable in lung and peripheral leukocyte According to PubMed:10945465, highly expressed in most brain areas examined, with the highest levels observed in corpus callosum, caudate nucleus, putamen, substantia nigra, thalamus, hippocampus, and spinal chord as well as in dorsal root ganglia (DRG). In the periphery, expression levels are relatively low, compared to the CNS, with the strongest expression detected in pancreas, testis, uterus, and stomach.|
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Provided below are standard protocols that you may find useful for product applications.
Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
Braeuner-Osborne H.,et al.Genomics 65:121-128(2000).
Robbins M.J.,et al.Genomics 67:8-18(2000).
Wei H.,et al.Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.
Cool B.H.,et al.Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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