|Application ||IHC-P, E|
|Dilution||IHC-P (20 µg/ml)|
|Other Names||Neuromedin-U receptor 2, NMU-R2, G-protein coupled receptor FM-4, G-protein coupled receptor TGR-1, NMUR2, NMU2R, TGR1|
|Target/Specificity||Human NMUR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||NMUR2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for the neuromedin-U and neuromedin-S neuropeptides.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Predominantly expressed in the CNS, particularly in the medulla oblongata, pontine reticular formation, spinal cord, and thalamus. High level in testis whereas lower levels are present in a variety of peripheral tissues including the gastrointestinal tract, genitourinary tract, liver, pancreas, adrenal gland, thyroid gland, lung, trachea, spleen and thymus.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for the neuromedin-U and neuromedin-S neuropeptides.
Hosoya M.,et al.J. Biol. Chem. 275:29528-29532(2000).
Raddatz R.,et al.J. Biol. Chem. 275:32452-32459(2000).
Shan L.,et al.J. Biol. Chem. 275:39482-39486(2000).
Schmutz J.,et al.Nature 431:268-274(2004).
Howard A.D.,et al.Nature 406:70-74(2000).
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