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RXFP1/ LGR7 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - RXFP1/ LGR7 Antibody (C-Terminus) ALS10132
    Anti-RXFP1/ LGR7 antibody IHC of human Breast, Carcinoma.
  • IHC - RXFP1/ LGR7 Antibody (C-Terminus) ALS10132
    Anti-RXFP1/ LGR7 antibody IHC of human Prostate, Carcinoma.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q9HBX9
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 87kDa
Dilution IHC-P (12 µg/ml)
Additional Information
Gene ID 59350
Other Names Relaxin receptor 1, Leucine-rich repeat-containing G-protein coupled receptor 7, Relaxin family peptide receptor 1, RXFP1, LGR7
Target/Specificity Human RXFP1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ANGPT2 (47%).
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsRXFP1/ LGR7 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RXFP1
Synonyms LGR7
Function Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen.
Volume 50 µl
Research Areas
Citations (0)

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Background

Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.

References

Hsu S.Y.,et al.Mol. Endocrinol. 14:1257-1271(2000).
Muda M.,et al.Mol. Hum. Reprod. 11:591-600(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS10132
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