|Dilution||IHC-P (1.25-2.5 µg/ml)|
|Other Names||cAMP-specific 3', 5'-cyclic phosphodiesterase 7B, 220.127.116.11, PDE7B|
|Target/Specificity||Human PDE7B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||PDE7B Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain.|
|Tissue Location||Highly expressed in brain. Also expressed in heart, liver, skeletal muscle and pancreas|
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Provided below are standard protocols that you may find useful for product applications.
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain.
Sasaki T.,et al.Biochem. Biophys. Res. Commun. 271:575-583(2000).
Gardner C.E.,et al.Biochem. Biophys. Res. Commun. 272:186-192(2000).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
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