|Reactivity||Human, Mouse, Rabbit, Hamster, Monkey, Horse, Bovine, Dog|
|Dilution||IHC-P (5 µg/ml)|
|Other Names||Calcium/calmodulin-dependent 3', 5'-cyclic nucleotide phosphodiesterase 1C, Cam-PDE 1C, 220.127.116.11, hCam-3, PDE1C|
|Target/Specificity||Human PDE1C. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||PDE1C Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP.|
|Tissue Location||Expressed in several tissues, including brain and heart|
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Provided below are standard protocols that you may find useful for product applications.
Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP.
Loughney K.,et al.J. Biol. Chem. 271:796-806(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
Oppermann F.S.,et al.Mol. Cell. Proteomics 8:1751-1764(2009).
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