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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   GPCR Antibodies   >   CXCR2 Antibody (N-Terminus)   

CXCR2 Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - CXCR2 Antibody (N-Terminus) ALS10170
    Anti-CXCR2 antibody ALS10170 IHC of human spleen.
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  • IHC - CXCR2 Antibody (N-Terminus) ALS10170
    Anti-CXCR2 antibody IHC of human Skin, Melanoma.
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  • IHC - CXCR2 Antibody (N-Terminus) ALS10170
    Anti-CXCR2 antibody IHC of human Brain, Glioblastoma.
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  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P25025
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 41kDa
Dilution IHC-P (5-10 µg/ml)
Additional Information
Gene ID 3579
Other Names C-X-C chemokine receptor type 2, CXC-R2, CXCR-2, CDw128b, GRO/MGSA receptor, High affinity interleukin-8 receptor B, IL-8R B, IL-8 receptor type 2, CD182, CXCR2, IL8RB
Target/Specificity Human CXCR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsCXCR2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CXCR2
Synonyms IL8RB
Function Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor (PubMed:1891716). Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G- protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:8662698). Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Cellular Location Cell membrane; Multi-pass membrane protein.
Research Areas
Citations (0)
citation

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Background

Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.

References

Murphy P.M.,et al.Science 253:1280-1283(1991).
Cerretti D.P.,et al.Mol. Immunol. 30:359-367(1993).
Sprenger H.,et al.J. Biol. Chem. 269:11065-11072(1994).
Ahuja S.K.,et al.J. Biol. Chem. 269:26381-26389(1994).
Kato H.,et al.Genes Immun. 1:330-337(2000).

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$ 467.50
Cat# ALS10170
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