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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   GPCR Antibodies   >   CXCR1 Antibody (Internal)   

CXCR1 Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IHC - CXCR1 Antibody (Internal) ALS10172
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  • IHC - CXCR1 Antibody (Internal) ALS10172
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  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P25024
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 40kDa
Dilution IHC-P (15-20 µg/ml)
Additional Information
Gene ID 3577
Other Names C-X-C chemokine receptor type 1, CXC-R1, CXCR-1, CDw128a, High affinity interleukin-8 receptor A, IL-8R A, IL-8 receptor type 1, CD181, CXCR1, CMKAR1, IL8RA
Target/Specificity Human CXCR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except CXCR2 (50%).
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsCXCR1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CXCR1
Synonyms CMKAR1, IL8RA
Function Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.
Cellular Location Cell membrane; Multi-pass membrane protein.
Volume 50 µl
Research Areas
Citations (0)

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Background

Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.

References

Holmes W.E.,et al.Science 253:1278-1280(1991).
Cerretti D.P.,et al.Mol. Immunol. 30:359-367(1993).
Mollereau C.,et al.Genomics 16:248-251(1993).
Ahuja S.K.,et al.J. Biol. Chem. 269:26381-26389(1994).
Liu Y.,et al.J. Mol. Evol. 61:691-696(2005).

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$ 395.00
Cat# ALS10172
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