|Dilution||IHC-P (2.5 µg/ml)|
|Other Names||Lysophosphatidic acid receptor 6, LPA receptor 6, LPA-6, Oleoyl-L-alpha-lysophosphatidic acid receptor, P2Y purinoceptor 5, P2Y5, Purinergic receptor 5, RB intron encoded G-protein coupled receptor, LPAR6, P2RY5|
|Target/Specificity||Human LPAR6 / P2RY5. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||LPAR6 / P2RY5 / P2Y5 Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds to oleoyl-L-alpha-lysophosphatidic acid (LPA). Intracellular cAMP is involved in the receptor activation. Important for the maintenance of hair growth and texture.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Expressed ubiquitously, including in skin and hair follicle cells. Detected in both Henle's and Huxley's layers of the inner root sheath of the hair follicle and in suprabasal layers of the epidermis (at protein level). Expressed at low levels in peripheral blood leukocytes|
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Provided below are standard protocols that you may find useful for product applications.
Binds to oleoyl-L-alpha-lysophosphatidic acid (LPA). Intracellular cAMP is involved in the receptor activation. Important for the maintenance of hair growth and texture.
Toguchida J.,et al.Genomics 17:535-543(1993).
Herzog H.,et al.Genome Res. 6:858-861(1996).
Bohm S.K.,et al.Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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