|Dilution||IHC-P (8-16 µg/ml)|
|Other Names||P2Y purinoceptor 11, P2Y11, P2RY11|
|Target/Specificity||Human P2RY11 / P2Y11. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||P2RY11 / P2Y11 Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Highest expression in liver and spleen.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP.
Communi D.,et al.J. Biol. Chem. 276:16561-16566(2001).
King M.M.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Communi D.,et al.J. Biol. Chem. 272:31969-31973(1997).
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