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GRM2 / MGLUR2 Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - GRM2 / MGLUR2 Antibody (N-Terminus) ALS10201
    Anti-GRM2 / MGLUR2 antibody ALS10201 IHC of human brain, neurons and glia.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q14416
Reactivity Human, Rabbit, Hamster
Host Rabbit
Clonality Polyclonal
Calculated MW 96kDa
Dilution IHC-P (19 µg/ml)
Additional Information
Gene ID 2912
Other Names Metabotropic glutamate receptor 2, mGluR2, GRM2, GPRC1B, MGLUR2
Target/Specificity Human GRM2 / MGLUR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsGRM2 / MGLUR2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRM2
Synonyms GPRC1B, MGLUR2
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell junction, synapse. Cell projection, dendrite
Tissue Location Detected in brain cortex (at protein level). Widely expressed in different regions of the adult brain as well as in fetal brain.
Volume 50 µl
Research Areas
Citations (0)

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Background

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.

References

Flor P.J.,et al.Eur. J. Neurosci. 7:622-629(1995).
Yasuyuki F.,et al.Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
Bonner T.I.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Kaighin V.A.,et al.Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS10201
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