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GRM7 / MGLUR7 Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - GRM7 / MGLUR7 Antibody (N-Terminus) ALS10206
    Anti-GRM7 / MGLUR7 antibody ALS10206 IHC of human brain, neurons and glia.
  • IHC - GRM7 / MGLUR7 Antibody (N-Terminus) ALS10206
    Anti-GRM7 / MGLUR7 antibody IHC of human adrenal.
  • IHC - GRM7 / MGLUR7 Antibody (N-Terminus) ALS10206
    Anti-GRM7 / MGLUR7 antibody IHC of human Skin, Melanoma.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC
Primary Accession Q14831
Reactivity Human, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 102kDa
Dilution IHC-P (6-16 µg/ml)
Additional Information
Gene ID 2917
Other Names Metabotropic glutamate receptor 7, mGluR7, GRM7, GPRC1G, MGLUR7
Target/Specificity Human GRM7 / MGLUR7. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GRM8 (63%).
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsGRM7 / MGLUR7 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRM7
Synonyms GPRC1G, MGLUR7
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed in many areas of the brain, especially in the cerebral cortex, hippocampus, and cerebellum Expression of GRM7 isoforms in non-neuronal tissues appears to be restricted to isoform 3 and isoform 4
Volume 50 µl
Research Areas
Citations (0)

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Background

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

References

Makoff A.,et al.Brain Res. Mol. Brain Res. 40:165-170(1996).
Flor P.J.,et al.Neuropharmacology 36:153-159(1997).
Wu S.,et al.Brain Res. Mol. Brain Res. 53:88-97(1998).
Schulz H.L.,et al.Neurosci. Lett. 326:37-40(2002).
Bolonna A.A.,et al.Schizophr. Res. 47:99-103(2001).

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$ 395.00
Cat# ALS10206
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