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GRM8 / MGLUR8 Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - GRM8 / MGLUR8 Antibody (N-Terminus) ALS10207
    Anti-GRM8 / MGLUR8 antibody IHC of human heart.
    detail
  • IHC - GRM8 / MGLUR8 Antibody (N-Terminus) ALS10207
    Anti-GRM8 / MGLUR8 antibody IHC of human brain, cortex.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, ICC
Primary Accession O00222
Reactivity Human, Mouse, Rabbit, Hamster, Monkey, Chicken, Sheep, Horse, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 102kDa
Dilution IHC-P (6 µg/ml)
Additional Information
Gene ID 2918
Other Names Metabotropic glutamate receptor 8, mGluR8, GRM8, GPRC1H, MGLUR8
Target/Specificity Human GRM8 / MGLUR8. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GRM7 (56%).
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsGRM8 / MGLUR8 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRM8
Synonyms GPRC1H, MGLUR8
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
Cellular Location Cell membrane; Multi-pass membrane protein.
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

References

Scherer S.W.,et al.Genomics 44:232-236(1997).
Wu S.,et al.Brain Res. Mol. Brain Res. 53:88-97(1998).
Malherbe P.,et al.Brain Res. Mol. Brain Res. 67:201-210(1999).
Stormann T.M.,et al.Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
Kaighin V.A.,et al.Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.

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$ 467.50
Cat# ALS10207
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