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NTSR1 / NTR Antibody (Cytoplasmic Domain)

Rabbit Polyclonal Antibody

     
  • IHC - NTSR1 / NTR Antibody (Cytoplasmic Domain) ALS10213
    Anti-NTSR1 / NTR antibody IHC of human Adrenal, Pheochromocytoma.
    detail
  • IHC - NTSR1 / NTR Antibody (Cytoplasmic Domain) ALS10213
    Anti-NTSR1 / NTR antibody IHC of human Bladder, Carcinoma.
    detail
  • IHC - NTSR1 / NTR Antibody (Cytoplasmic Domain) ALS10213
    Anti-NTSR1 antibody ALS10213 IHC of human brain, neurons and glia.
    detail
  • IHC - NTSR1 / NTR Antibody (Cytoplasmic Domain) ALS10213
    Anti-NTSR1 / NTR antibody IHC of human Lung, Adenocarcinoma.
    detail
  • IHC - NTSR1 / NTR Antibody (Cytoplasmic Domain) ALS10213
    Anti-NTSR1 / NTR antibody IHC of human Ovary, Carcinoma.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P30989
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 46kDa
Dilution IHC-P (16 µg/ml)
Additional Information
Gene ID 4923
Other Names Neurotensin receptor type 1, NT-R-1, NTR1, High-affinity levocabastine-insensitive neurotensin receptor, NTRH, NTSR1, NTRR
Target/Specificity Human NTSR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsNTSR1 / NTR Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NTSR1
Synonyms NTRR
Function G-protein coupled receptor for the tridecapeptide neurotensin (NTS) (PubMed:8381365, PubMed:21725197, PubMed:23140271). Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system. Signaling leads to the activation of downstream MAP kinases and protects cells against apoptosis (PubMed:21725197).
Cellular Location Cell membrane; Multi-pass membrane protein. Membrane raft. Note=Palmitoylation is required for localization at CAV1-enriched membrane rafts
Tissue Location Expressed in prostate (at protein level). Detected in colon and peripheral blood mononuclear cells. Detected at very low levels in brain.
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

G-protein coupled receptor for the tridecapeptide neurotensin (NTS). Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system. Signaling leads to the activation of downstream MAP kinases and protects cells against apoptosis.

References

Vita N.,et al.FEBS Lett. 317:139-142(1993).
Kopatz S.A.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
Deloukas P.,et al.Nature 414:865-871(2001).
Swift S.L.,et al.Cancer Res. 70:347-356(2010).
Heakal Y.,et al.Cancer Biol. Ther. 12:427-435(2011).

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$ 467.50
Cat# ALS10213
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