|Dilution||IHC-P (5-7 µg/ml)|
|Other Names||Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R, MC1R, MSHR|
|Target/Specificity||Human MC1 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||MC1R Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Melanocytes and corticoadrenal tissue.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Mountjoy K.G.,et al.Science 257:1248-1251(1992).
Gantz I.,et al.J. Biol. Chem. 268:8246-8250(1993).
Chhajlani V.,et al.FEBS Lett. 309:417-420(1992).
Chhajlani V.,et al.FEBS Lett. 390:238-238(1996).
Rana B.K.,et al.Genetics 151:1547-1557(1999).
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