|Reactivity||Human, Monkey, Horse, Xenopus|
|Dilution||IHC-P (9-17 µg/ml)|
|Other Names||RPE-retinal G protein-coupled receptor, RGR|
|Target/Specificity||Human RGR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||RGR Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for all-trans- and 11-cis-retinal. Binds preferentially to the former and may catalyze the isomerization of the chromophore by a retinochrome-like mechanism.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Preferentially expressed at high levels in the retinal pigment epithelium (RPE) and Mueller cells of the neural retina|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for all-trans- and 11-cis-retinal. Binds preferentially to the former and may catalyze the isomerization of the chromophore by a retinochrome-like mechanism.
Shen D.,et al.Biochemistry 33:13117-13125(1994).
Deloukas P.,et al.Nature 429:375-381(2004).
Morimura H.,et al.Nat. Genet. 23:393-394(1999).
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