|Reactivity||Human, Monkey, Horse|
|Calculated MW||42195 Da|
|Dilution||IHC-P (4 µg/ml)|
|Other Names||Neuropeptide Y receptor type 4, NPY4-R, Pancreatic polypeptide receptor 1, PP1, NPY4R, PPYR1|
|Target/Specificity||Human PPYR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||NPY4R / PPYR1 Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13- 36) > PP (31-36) > NPY free acid.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Highest levels found in brain, coronary artery and ileum. Low levels in pancreas and kidney. Detected in colon and small intestine|
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