|Reactivity||Human, Mouse, Hamster, Monkey|
|Dilution||IHC-P (3-5 µg/ml)|
|Other Names||Neuropeptide Y receptor type 5, NPY5-R, NPY-Y5 receptor, NPYY5-R, Y5 receptor, NPY5R, NPYR5|
|Target/Specificity||Human NPY5R. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||NPY5R Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Brain; hypothalamus.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.
Hu Y.,et al.J. Biol. Chem. 271:26315-26319(1996).
Gerald C.,et al.Nature 382:168-171(1996).
Herzog H.,et al.Genomics 41:315-319(1997).
Kopatz S.A.,et al.Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
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