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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ADGRL1 / LPHN1 Antibody (N-Terminus)   

ADGRL1 / LPHN1 Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - ADGRL1 / LPHN1 Antibody (N-Terminus) ALS10275
    Anti-LPHN1 antibody ALS10275 IHC of human brain, neurons and glia.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession O94910
Reactivity Human, Mouse, Rabbit, Hamster, Monkey, Pig, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 163kDa
Dilution IHC-P (8 µg/ml)
Additional Information
Gene ID 22859
Other Names Latrophilin-1, Calcium-independent alpha-latrotoxin receptor 1, CIRL-1, Lectomedin-2, LPHN1, KIAA0821, LEC2
Target/Specificity Human LPHN1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsADGRL1 / LPHN1 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADGRL1 (HGNC:20973)
Function Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein. Cell projection, axon {ECO:0000250|UniProtKB:O88917}. Cell projection, growth cone {ECO:0000250|UniProtKB:O88917}. Cell junction, synapse {ECO:0000250|UniProtKB:O88917}. Cell junction, synapse, presynaptic cell membrane {ECO:0000250|UniProtKB:O88917} Cell junction, synapse, synaptosome {ECO:0000250|UniProtKB:O88917}. Note=Colocalizes with TENM2 on the cell surface, across intercellular junctions and on nerve terminals near synaptic clefts. {ECO:0000250|UniProtKB:O88917}
Volume 50 µl
Research Areas
Citations (0)

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Background

Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor propably implicated in the regulation of exocytosis (By similarity).

References

Douangpanya J.,et al.Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
Nagase T.,et al.DNA Res. 5:355-364(1998).
Suwa M.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
Brill L.M.,et al.Anal. Chem. 76:2763-2772(2004).

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$ 395.00
Cat# ALS10275
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