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TACR1 / NK1R Antibody (Extracellular Domain)

Rabbit Polyclonal Antibody

     
  • IHC - TACR1 /  NK1R Antibody (Extracellular Domain) ALS10340
    Anti-Neurokinin 1 Receptor antibody ALS10340 IHC of human brain, neurons and glia.
  • IHC - TACR1 /  NK1R Antibody (Extracellular Domain) ALS10340
    Anti-TACR1 / NK1R antibody IHC of human Brain, Glioblastoma.
  • IHC - TACR1 /  NK1R Antibody (Extracellular Domain) ALS10340
    Anti-TACR1 / NK1R antibody IHC of human Lung, Adenocarcinoma.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P25103
Reactivity Human, Monkey, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 46kDa
Dilution IHC-P (2-4 µg/ml)
Additional Information
Gene ID 6869
Other Names Substance-P receptor, SPR, NK-1 receptor, NK-1R, Tachykinin receptor 1, TACR1, NK1R, TAC1R
Target/Specificity Human Neurokinin 1 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsTACR1 / NK1R Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TACR1
Synonyms NK1R, TAC1R
Function This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
Cellular Location Cell membrane; Multi-pass membrane protein.
Volume 50 µl
Research Areas
Citations (0)

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Background

This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.

References

Takeda Y.,et al.Biochem. Biophys. Res. Commun. 179:1232-1240(1991).
Hopkins B.,et al.Biochem. Biophys. Res. Commun. 180:1110-1117(1991).
Gerard N.P.,et al.Biochemistry 30:10640-10646(1991).
Takahashi K.,et al.Eur. J. Biochem. 204:1025-1033(1992).
Fong T.M.,et al.Mol. Pharmacol. 41:24-30(1992).

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$ 395.00
Cat# ALS10340
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