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Leukotriene B4 Receptor / BLT1 Antibody (Cytoplasmic Domain)

Rabbit Polyclonal Antibody

     
  • IHC - Leukotriene B4 Receptor / BLT1 Antibody (Cytoplasmic Domain) ALS10373
    Anti-Leukotriene B4 Receptor antibody ALS10373 IHC of human spleen, red pulp.
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q15722
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 38kDa
Dilution IHC-P (20 µg/ml)
Additional Information
Gene ID 1241
Other Names Leukotriene B4 receptor 1, LTB4-R 1, LTB4-R1, Chemoattractant receptor-like 1, G-protein coupled receptor 16, P2Y purinoceptor 7, P2Y7, LTB4R, BLT, BLT1, BLTR, CMKRL1, GPR16, P2RY7
Target/Specificity Human Leukotriene B4 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsLeukotriene B4 Receptor / BLT1 Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LTB4R
Synonyms BLT, BLT1, BLTR, CMKRL1, GPR16, P2RY7
Function Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues
Volume 50 µl
Research Areas
Citations (0)

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Background

Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.

References

Akbar G.K.M.,et al.J. Biol. Chem. 271:18363-18367(1996).
Raport C.J.,et al.J. Leukoc. Biol. 59:18-23(1996).
Yokomizo T.,et al.Nature 387:620-624(1997).
Owman C.S.O.,et al.Genomics 37:187-194(1996).
Kato K.,et al.J. Exp. Med. 192:413-420(2000).

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$ 395.00
Cat# ALS10373
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