Aggrecan Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | P16112 |
Reactivity | Human, Hamster, Monkey, Pig |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 261329 Da |
Dilution | IHC-P (7 µg/ml) |
Gene ID | 176 |
---|---|
Other Names | Aggrecan core protein, Cartilage-specific proteoglycan core protein, CSPCP, Chondroitin sulfate proteoglycan core protein 1, Chondroitin sulfate proteoglycan 1, Aggrecan core protein 2, ACAN, AGC1, CSPG1, MSK16 |
Target/Specificity | Human ACAN / Aggrecan. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except NCAN (56%). |
Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
Precautions | Aggrecan Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ACAN |
---|---|
Synonyms | AGC1, CSPG1, MSK16 |
Function | This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. |
Cellular Location | Secreted, extracellular space, extracellular matrix |
Tissue Location | Detected in fibroblasts (at protein level) (PubMed:36213313). Restricted to cartilage (PubMed:7524681) |
Volume | 50 µl |
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