|Reactivity||Human, Hamster, Monkey, Pig|
|Calculated MW||250193 Da|
|Dilution||IHC-P (7 µg/ml)|
|Other Names||Aggrecan core protein, Cartilage-specific proteoglycan core protein, CSPCP, Chondroitin sulfate proteoglycan core protein 1, Chondroitin sulfate proteoglycan 1, Aggrecan core protein 2, ACAN, AGC1, CSPG1, MSK16|
|Target/Specificity||Human ACAN / Aggrecan. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except NCAN (56%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||Aggrecan Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||AGC1, CSPG1, MSK16|
|Function||This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
|Tissue Location||Restricted to cartilages.|
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