|Dilution||IHC-P (20-40 µg/ml)|
|Other Names||P2Y purinoceptor 13, P2Y13, G-protein coupled receptor 86, G-protein coupled receptor 94, P2RY13, GPR86, GPR94|
|Target/Specificity||Human P2RY13 / P2Y13. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PRPF4B (50%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||P2Y13 / P2RY13 Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Strong expression in spleen and adult brain. Lower expression in placenta, lung, liver, spinal cord, thymus, small intestine, uterus, stomach, testis, fetal brain, and adrenal gland. Not detected in pancreas, heart, kidney, skeletal muscle, ovary or fetal aorta. Clearly detected in lymph node and bone marrow, weakly detected in peripheral blood mononuclear cells (PBMC) and in peripheral blood leukocytes (PBL), but not detected in polymorphonuclear cells (PMN). In the brain, detected in all brain regions examined|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system.
Lee D.K.,et al.Gene 275:83-91(2001).
Communi D.,et al.J. Biol. Chem. 276:41479-41485(2001).
Wittenberger T.,et al.J. Mol. Biol. 307:799-813(2001).
Wang Y.-G.,et al.Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
Takeda S.,et al.FEBS Lett. 520:97-101(2002).
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