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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GPR61 Antibody (C-Terminus)   

GPR61 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - GPR61 Antibody (C-Terminus) ALS10431
    Anti-GPR61 antibody ALS10431 IHC of human brain, cortex.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q9BZJ8
Reactivity Human, Monkey
Host Rabbit
Clonality Polyclonal
Calculated MW 49kDa
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 83873
Other Names Probable G-protein coupled receptor 61, Biogenic amine receptor-like G-protein coupled receptor, GPR61, BALGR
Target/Specificity Human GPR61. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsGPR61 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GPR61
Synonyms BALGR {ECO:0000303|PubMed:11690637}, GPC
Function Orphan G-protein coupled receptor. Constitutively activates the G(s)-alpha/cAMP signaling pathway (PubMed:28827538). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (PubMed:28827538). May be involved in the regulation of food intake and body weight (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Note=Colocalizes with ARRB2/beta-arrestin-2 in the endosome (PubMed:28827538)
Tissue Location Expressed in brain; detected in frontal and temporal lobes, occipital pole, amygdala and hippocampus (PubMed:11690637, PubMed:29226084). Also expressed in testis (PubMed:11690637, PubMed:29226084) and T cells, B cells, and monocyte (PubMed:29226084). Low expression in many other tissues (PubMed:11690637, PubMed:29226084). Widely expressed in the hippocampus (at protein level).
Volume 50 µl
Research Areas
Citations (0)

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Background

Orphan receptor.

References

Lee D.K.,et al.Brain Res. Mol. Brain Res. 86:13-22(2001).
Cikos S.,et al.Biochim. Biophys. Acta 1521:66-72(2001).
Takeda S.,et al.FEBS Lett. 520:97-101(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).

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$ 425.00
Cat# ALS10431
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