|Dilution||IHC-P (5-10 µg/ml)|
|Other Names||Melanin-concentrating hormone receptor 2, MCH receptor 2, MCH-R2, MCHR-2, G-protein coupled receptor 145, GPRv17, MCH-2R, MCH2, MCH2R, MCHR2, GPR145, SLT|
|Target/Specificity||Human MCHR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||MCHR2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Specifically expressed in the brain, with highest levels in cerebral cortex, hippocampus and amygdala. No expression detected in the cerebellum, thalamus or hypothalamus|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis.
Mori M.,et al.Biochem. Biophys. Res. Commun. 283:1013-1018(2001).
Sailer A.W.,et al.Proc. Natl. Acad. Sci. U.S.A. 98:7564-7569(2001).
Wang S.,et al.J. Biol. Chem. 276:34664-34670(2001).
Hill J.,et al.J. Biol. Chem. 276:20125-20129(2001).
Kurama T.,et al.Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
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