|Reactivity||Human, Pig, Horse, Bovine, Dog|
|Dilution||IHC-P (6 µg/ml)|
|Other Names||Taste receptor type 1 member 1, G-protein coupled receptor 70, TAS1R1, GPR70, T1R1, TR1|
|Target/Specificity||Human TAS1R1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except TAS1R2 (69%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||T1R1 / TAS1R1 Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||GPR70, T1R1, TR1|
|Function||Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.
Suwa M.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
Makalowska I.,et al.Gene 284:203-213(2002).
Li X.,et al.Proc. Natl. Acad. Sci. U.S.A. 99:4692-4696(2002).
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