|Dilution||IHC-P (7-14 µg/ml)|
|Other Names||Follicle-stimulating hormone receptor, FSH-R, Follitropin receptor, FSHR, LGR1|
|Target/Specificity||Human FSHR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||FSH Receptor / FSHR Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Induces cAMP production through the activation of PI3K-AKT and SRC-ERK1/2 signaling pathways.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Sertoli cells and ovarian granulosa cells.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Minegish T.,et al.Biochem. Biophys. Res. Commun. 175:1125-1130(1991).
Tilly J.L.,et al.Endocrinology 131:799-806(1992).
Kelton C.A.,et al.Mol. Cell. Endocrinol. 89:141-151(1992).
Liu X.,et al.Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
Kopatz S.A.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
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