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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   NR5A2 / LRH-1 Antibody (C-Terminus)   

NR5A2 / LRH-1 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - NR5A2 / LRH-1 Antibody (C-Terminus) ALS10549
    Anti-LRH-1 / NR5A2 antibody IHC of human testis.
  • IHC - NR5A2 / LRH-1 Antibody (C-Terminus) ALS10549
    Anti-LRH-1 / NR5A2 antibody IHC of human adipocytes.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession O00482
Reactivity Human, Monkey, Pig, Sheep, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 61kDa
Dilution IHC-P (7 µg/ml)
Additional Information
Gene ID 2494
Other Names Nuclear receptor subfamily 5 group A member 2, Alpha-1-fetoprotein transcription factor, B1-binding factor, hB1F, CYP7A promoter-binding factor, Hepatocytic transcription factor, Liver receptor homolog 1, LRH-1, NR5A2, B1F, CPF, FTF
Target/Specificity Human NR5A2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsNR5A2 / LRH-1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NR5A2
Synonyms B1F, CPF, FTF
Function Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
Cellular Location Nucleus.
Tissue Location Abundantly expressed in pancreas, less in liver, very low levels in heart and lung. Expressed in the Hep-G2 cell line. Isoform 1 and isoform 2 seem to be present in fetal and adult liver and Hep-G2 cells
Volume 50 µl
Research Areas
Citations (0)

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Background

Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.

References

Li M.,et al.J. Biol. Chem. 273:29022-29031(1998).
Li M.,et al.Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases.
Nitta M.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:6660-6665(1999).
Zhang C.K.,et al.Gene 273:239-249(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS10549
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