|Dilution||IHC-P (10-15 µg/ml)|
|Other Names||Somatostatin receptor type 3, SS-3-R, SS3-R, SS3R, SSR-28, SSTR3|
|Target/Specificity||Human SSTR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||SSTR3 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Note=Internalized into endoplasmic vesicles upon somatostatin-stimulation.|
|Tissue Location||Brain, pituitary and pancreas.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.
Yamada Y.,et al.Mol. Endocrinol. 6:2136-2142(1992).
Corness J.D.,et al.FEBS Lett. 321:279-284(1993).
Rasch A.C.,et al.Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
Kopatz S.A.,et al.Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004).
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