|Dilution||IHC-P (10 µg/ml)|
|Other Names||Somatostatin receptor type 5, SS-5-R, SS5-R, SS5R, SSTR5|
|Target/Specificity||Human SSTR5. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||SSTR5 Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SSTR2 following heterodimerization.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus. No expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SSTR2 following heterodimerization.
Panetta R.,et al.Mol. Pharmacol. 45:417-427(1994).
Yamada Y.,et al.Biochem. Biophys. Res. Commun. 195:844-852(1993).
O'Carroll A.-M.,et al.Mol. Pharmacol. 46:291-298(1994).
Petersenn S.,et al.Endocrinology 143:2626-2634(2002).
Daniels R.J.,et al.Hum. Mol. Genet. 10:339-352(2001).
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