|Dilution||IHC-P (3-16 µg/ml)|
|Other Names||Mas-related G-protein coupled receptor member X4, Sensory neuron-specific G-protein coupled receptor 5/6, MRGPRX4, MRGX4, SNSR5, SNSR6|
|Target/Specificity||Human MRGPRX4 / MRGX4. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MRGPRX3 (67%), MRGPRX1 (67%), ALMS1 (44%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||MRGPRX4 / MRGX4 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||MRGX4, SNSR5, SNSR6|
|Function||Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity).
Dong X.,et al.Cell 106:619-632(2001).
Lembo P.M.C.,et al.Nat. Neurosci. 5:201-209(2002).
Taylor T.D.,et al.Nature 440:497-500(2006).
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