|Dilution||IHC-P (3-16 µg/ml)|
|Other Names||Mas-related G-protein coupled receptor member X4, Sensory neuron-specific G-protein coupled receptor 5/6, MRGPRX4, MRGX4, SNSR5, SNSR6|
|Target/Specificity||Human MRGPRX4 / MRGX4. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MRGPRX3 (67%), MRGPRX1 (67%), ALMS1 (44%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||MRGPRX4 / MRGX4 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||MRGX4, SNSR5, SNSR6|
|Function||Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons|
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Provided below are standard protocols that you may find useful for product applications.
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity).
Dong X.,et al.Cell 106:619-632(2001).
Lembo P.M.C.,et al.Nat. Neurosci. 5:201-209(2002).
Taylor T.D.,et al.Nature 440:497-500(2006).
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