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SLC5A4 / SGLT2 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - SLC5A4 / SGLT2 Antibody (C-Terminus) ALS10585
    Anti-SLC5A4 antibody ALS10585 IHC of human liver.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q9NY91
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 72kDa
Dilution IHC-P (20 µg/ml)
Additional Information
Gene ID 6527
Other Names Low affinity sodium-glucose cotransporter, Sodium/glucose cotransporter 3, Na(+)/glucose cotransporter 3, Solute carrier family 5 member 4, SLC5A4, SAAT1, SGLT2
Target/Specificity Human SLC5A4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsSLC5A4 / SGLT2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC5A4 {ECO:0000303|PubMed:13130073}
Function Does not function as sodium/D-glucose symporter (PubMed:13130073, PubMed:20421923, PubMed:22766068). However, may function as a D-glucose sensor by generating a D-glucose-induced depolarization which is pH-independent, Na(+)-dependent at neutral pH and probably H(+)-dependent at acidic pH (PubMed:13130073, PubMed:22766068, PubMed:17110502, PubMed:20421923).
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Expressed in skeletal muscle, where it may localize to the neuromuscular junction (at protein level) (PubMed:13130073) Expressed in small intestine where it may localize to cholinergic neurons of the submucosal plexus and myenteric plexus (at protein level) (PubMed:13130073). Detected in kidney (at protein level) (PubMed:22766068).
Volume 50 µl
Research Areas
Citations (0)
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Background

Sodium-dependent glucose transporter.

References

Gorboulev V.,et al.Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
Dunham I.,et al.Nature 402:489-495(1999).
Poppe R.,et al.Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.

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$ 467.50
Cat# ALS10585
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