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INPP5J / PIB5PA Antibody (Internal)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | Q15735 |
| Reactivity | Human, Pig, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 107kDa |
| Dilution | IHC-P (10-15 µg/ml) |
| Gene ID | 27124 |
|---|---|
| Other Names | Phosphatidylinositol 4, 5-bisphosphate 5-phosphatase A, 3.1.3.56, Inositol polyphosphate 5-phosphatase J, INPP5J, PIB5PA, PIPP |
| Target/Specificity | Human INPP5J / PIB5PA. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | INPP5J / PIB5PA Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | INPP5J |
|---|---|
| Synonyms | PIB5PA, PIPP |
| Function | Inositol 5-phosphatase, which converts inositol 1,4,5- trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4- phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4- trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles. |
| Cellular Location | Cytoplasm. Note=Predominantly localized to membrane ruffles. |
| Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Inositol 5-phosphatase, which converts inositol 1,4,5- trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4- phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate- binding proteins that are present at membranes ruffles (By similarity).
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham I.,et al.Nature 402:489-495(1999).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Nussbaum R.L.,et al.Submitted (JAN-1996) to the EMBL/GenBank/DDBJ databases.
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